The economy of Cistérniga is primarily driven by its agricultural roots, as the town is located within one of Spain’s most fertile agricultural regions. Farming, particularly cereal crops, grapes, and vegetables, plays a major role in the local economy. The nearby Ribera del Duero wine region also influences the town’s economy, with local wineries and vineyards contributing to both tourism and commerce.
In recent years, Cistérniga has seen a growth in its service and hospitality sectors, thanks to its proximity to Valladolid. Event organizers often look to the town as a venue for hosting small to medium-sized gatherings, retreats, or cultural events. Additionally, local businesses, including crafts and small-scale manufacturing, play an important role in sustaining the town’s economy.